A friend/customer of mine, Rich, was having problems with his Lightroom 3.3 (current). It was as fast as molasses on a cold day.
I tried to help him over the phone, no luck. Time for TeamViewer. It's some software so I can log onto his computer without having me to drive there.
Yes, it's slow, very slow. A quick looking around, nothing too obvious. Switching to the Grid View is extremely slow. I start the task manager to see what's happening and I see a very high IO, it's the one in red. IO is Input/Output.